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kgn cells  (MedChemExpress)


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    Structured Review

    MedChemExpress kgn cells
    Kgn Cells, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 12 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/kgn+cells/4-Methylumbelliferone/pm42114679-70-50-66
    Average 94 stars, based on 12 article reviews
    kgn cells - by Bioz Stars, 2026-11
    94/100 stars

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    Related Articles

    Incubation:

    Article Title: MIT-001 ameliorates ferroptosis-induced mitochondrial dysfunction and enhances embryo quality in preimplantation embryos from aged female mice.
    Article Snippet: .. KGN cells were seeded in 6-well plates at a density of 5 × 105 cells/ well and incubated for 24 h. Cells were treated with MIT-001 (10 μM; MedChemExpress, Monmouth Junction, NJ, USA), resveratrol (50 μM, Selleckchem), mitoquinone (1 μM, Cayman Chemical), coenzyme Q10 (10 μM; Sigma-Aldrich, St. Louis, MO, USA), ferrostatin-1 (2 μM, Selleckchem), or liproxstatin-1 (2 μM, Selleckchem) for 20 min and were then exposed to RSL3 (1 μM, MedChemExpress) for 24 h. Proteins were extracted using NP-40 cell lysis buffer (Cat# FNN0021; Invitrogen, Waltham, MA, USA). ..

    Article Title: Comparative assessment of female reproductive toxicity from PFOA and its alternative GenX in mice and human granulosa cells.
    Article Snippet: Perfluorooctanoic acid (PFOA) is a legacy perfluoroalkyl substance (PFAS) with various detrimental health effects, prompting its replacement by hexafluoropropylene oxide dimer acid (GenX).. However, the female reproductive toxicity and underlying mechanism of GenX remain inadequately understood.. In this study, we comparatively evaluated the impacts of PFOA and GenX on ovarian function using integrated in vivo mouse and in vitro human granulosa cell models.

    Lysis:

    Article Title: MIT-001 ameliorates ferroptosis-induced mitochondrial dysfunction and enhances embryo quality in preimplantation embryos from aged female mice.
    Article Snippet: .. KGN cells were seeded in 6-well plates at a density of 5 × 105 cells/ well and incubated for 24 h. Cells were treated with MIT-001 (10 μM; MedChemExpress, Monmouth Junction, NJ, USA), resveratrol (50 μM, Selleckchem), mitoquinone (1 μM, Cayman Chemical), coenzyme Q10 (10 μM; Sigma-Aldrich, St. Louis, MO, USA), ferrostatin-1 (2 μM, Selleckchem), or liproxstatin-1 (2 μM, Selleckchem) for 20 min and were then exposed to RSL3 (1 μM, MedChemExpress) for 24 h. Proteins were extracted using NP-40 cell lysis buffer (Cat# FNN0021; Invitrogen, Waltham, MA, USA). ..

    Fluorescence:

    Article Title: Comparative assessment of female reproductive toxicity from PFOA and its alternative GenX in mice and human granulosa cells.
    Article Snippet: Perfluorooctanoic acid (PFOA) is a legacy perfluoroalkyl substance (PFAS) with various detrimental health effects, prompting its replacement by hexafluoropropylene oxide dimer acid (GenX).. However, the female reproductive toxicity and underlying mechanism of GenX remain inadequately understood.. In this study, we comparatively evaluated the impacts of PFOA and GenX on ovarian function using integrated in vivo mouse and in vitro human granulosa cell models.

    In Vitro:

    Article Title: Inhalation exposure to tire rubber particle-sourced pollutant 6PPD-quinone involving basolateral amygdala impairment in male ICR mice.
    Article Snippet: 39,810,414 Male SD rats Adult Not specified (HY-153169*) MedChemExpress Biotechnology Ltd. 0.4, 2, 4 mg/kg Every 4 days for 28 days Intraperitoneal injection Kidneys Renal tissue damage; Activation of MAPK pathway; Increased expression of NOTCH1, TP53, TNF, IL1B, IL6. .. 39,862,509 Female BALB/c mice, KGN cells 6-week-old (mice) Not specified (HY-153169*) MedChemExpress Biotechnology Ltd. 4 mg/kg (mice), 0.5– 50 ng/mL (cells) Every 3 days for 40 days Intraperitoneal (mice), in vitro (cells) Ovaries, granulosa cells PCOS-like changes; Granulosa cell apoptosis; Inhibition of PI3K/AKT/ FOXO1 pathway; Elevated 6PPD-Q in human follicular fluid. .. 39,764,971 Male C57BL/6 mice 4-week-old ≥95 % Alfa Chemical Co., Ltd. 4 mg/kg Every 4 days for 40 days Intraperitoneal injection Testes Reduced sperm quality; Germ cell apoptosis; Disrupted sphingolipid signaling pathway; Lower testosterone levels, impaired IVF outcomes.

    Inhibition:

    Article Title: Inhalation exposure to tire rubber particle-sourced pollutant 6PPD-quinone involving basolateral amygdala impairment in male ICR mice.
    Article Snippet: 39,810,414 Male SD rats Adult Not specified (HY-153169*) MedChemExpress Biotechnology Ltd. 0.4, 2, 4 mg/kg Every 4 days for 28 days Intraperitoneal injection Kidneys Renal tissue damage; Activation of MAPK pathway; Increased expression of NOTCH1, TP53, TNF, IL1B, IL6. .. 39,862,509 Female BALB/c mice, KGN cells 6-week-old (mice) Not specified (HY-153169*) MedChemExpress Biotechnology Ltd. 4 mg/kg (mice), 0.5– 50 ng/mL (cells) Every 3 days for 40 days Intraperitoneal (mice), in vitro (cells) Ovaries, granulosa cells PCOS-like changes; Granulosa cell apoptosis; Inhibition of PI3K/AKT/ FOXO1 pathway; Elevated 6PPD-Q in human follicular fluid. .. 39,764,971 Male C57BL/6 mice 4-week-old ≥95 % Alfa Chemical Co., Ltd. 4 mg/kg Every 4 days for 40 days Intraperitoneal injection Testes Reduced sperm quality; Germ cell apoptosis; Disrupted sphingolipid signaling pathway; Lower testosterone levels, impaired IVF outcomes.



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